Newer aspects of carnitine metabolism in uremia
| Autor: | Paolo Monardo, Agostino Mallamace, Vincenzo Savica, Paola Benatti, Guido Bellinghieri, Rodolfo Savica, Domenico Santoro, Menotti Calvani |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Renal Dialysis Internal medicine Carnitine Medicine Humans In patient Carnitine acyltransferase Carnitine deficiency Uremia Ejection fraction business.industry Maintenance hemodialysis medicine.disease Carnitine metabolism Mitochondria Endocrinology Hemodialysis Nephrology Erythropoietin Kidney Failure Chronic business medicine.drug |
| Zdroj: | Seminars in nephrology. 26(1) |
| ISSN: | 0270-9295 |
| Popis: | New knowledge on the physiologic role of L-carnitine and on the rationale of its use in patients on maintenance hemodialysis is provided. In particular, carnitine normalizes plasma and muscle carnitine levels and modifies both enzymatic pattern of muscle and morphology of single fibers, improving exercise tolerance. In addition, carnitine reduces erythropoietin requirements, the number of hypotensive episodes, improves ejection fraction, and decreases hospitalization. |
| Databáze: | OpenAIRE |
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