The Alpha-1 Adrenergic Blocking Agent Urapidil Counteracts Postrotational Atherectomy 'Elastic Recoil' Where Nitrates Have Failed

Autor: Jean Marco, Luisa Gregorini, G. Anguissola, M. Bernies, Guido Pomidossi, Bernard Cassagneau, Jean Fajadet
Rok vydání: 1997
Předmět:
Zdroj: ResearcherID
ISSN: 0002-9149
Popis: Calcium antagonist pretreatment and intracoronary high doses of nitrates (9 mg of isosorbide dinitrate) do not counteract coronary vasoconstriction occurring after rotational atherectomy. In 30 patients undergoing Rotablator atherectomy, intracoronary injection of the alpha 1-sympathetic blocker urapidil abolished or prevented significant vasoconstriction occurring 15 minutes after the procedure despite repeated injections of nitrates.
Databáze: OpenAIRE