Hand Radiological Damage in Systemic Sclerosis: Comparison with a Control Group and Clinical and Functional Correlations
| Autor: | Jacques Malghem, Filip De Keyser, Vanessa Smith, Rene Westhovens, Marie Vanthuyne, G Depresseux, Frédéric Houssiau, Ellen De Langhe, S. Koutaissoff |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Osteolysis Severity of Illness Index Scleroderma Arthritis Rheumatoid Disease activity Young Adult Rheumatology Internal medicine Osteoarthritis Arthropathy Humans Medicine skin and connective tissue diseases Aged Aged 80 and over Scleroderma Systemic integumentary system business.industry Calcinosis Middle Aged Hand medicine.disease Surgery Radiography Anesthesiology and Pain Medicine Case-Control Studies Radiological weapon Female business |
| Zdroj: | Seminars in Arthritis and Rheumatism. 40:455-460 |
| ISSN: | 0049-0172 |
| Popis: | To define the burden of hand radiological damage in systemic sclerosis (SSc) patients, compared with a control group.Both hands of 167 SSc patients and 168 hands (82 right and 86 left) of age- and gender-matched controls were imaged by conventional radiograph. Two musculoskeletal radiologists semiquantitatively scored the following lesions: tuft acro-osteolysis, tuft calcinosis, joint space narrowings, marginal erosions, surface erosions, collapse arthropathies, periarticular calcifications, and juxta-articular osteoporosis, at the following areas: tufts, distal interphalangeal, proximal interphalangeal, metacarpophalangeal, carpal, and first carpometacarpal joints. Clinical and functional characteristics of the 167 SSc patients were obtained from the Belgian Systemic Sclerosis Cohort database.Tuft acro-osteolysis and calcinosis were the most common findings observed in SSc patients and were almost absent in controls. SSc patients displaying tuft acro-osteolysis/calcinosis suffered from more severe disease. Arthropathies were infrequently detected and mainly consisted of a mixture of osteoarthritis-related changes (joint space narrowing and surface erosions)-also observed in controls-and of 2 types of rare SSc-associated arthropathies: a rheumatoid arthritis-like pattern, characterized by marginal erosions (n = 7 patients), and a collapse arthropathy (n = 6 patients), characterized by pressure erosions and joint subluxation.Although a rheumatoid arthritis-like or a collapse arthropathy can be observed in SSc patients, arthropathies are less common than previously reported. |
| Databáze: | OpenAIRE |
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