Histologic correlation between smartphone and coloposcopic findings in patients with abnormal cervical cytology: experiences in a tertiary referral hospital
Autor: | Reisa Kakubari, Satoko Matsuzaki, Yutaka Ueda, Shinya Matsuzaki, Tadashi Kimura, Mamoru Kakuda, Akiko Okazawa, Tomomi Egawa-Takata, Yusuke Tanaka, Satoshi Kubota, Eiji Kobayashi |
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Rok vydání: | 2018 |
Předmět: |
Adult
medicine.medical_specialty Uterine Cervical Neoplasms Gynecologic oncology Adenocarcinoma in Situ Tertiary referral hospital Sensitivity and Specificity Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Medicine Humans In patient 030212 general & internal medicine Medical diagnosis Colposcopy Vaginal Smears 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics Obstetrics and Gynecology Middle Aged Uterine Cervical Dysplasia Confidence interval Abnormal cervical cytology Carcinoma Squamous Cell Female Smartphone business Histological correlation Follow-Up Studies |
Zdroj: | American journal of obstetrics and gynecology. 221(3) |
ISSN: | 1097-6868 |
Popis: | Background Smartphones recently have been applied in the medical setting. However, the literature evaluating the utility of smartphones in gynecologic oncology is limited. Objective To evaluate the utility of a smartphone in the detection of uterine cervical lesions in patients with abnormal cervical cytology. Study Design Seventy-five women with abnormal cervical cytology were enrolled. Two doctors independently inspected the uterine cervix by using smartphone or colposcopy. Images were captured using acetic acid, and biopsies were taken as standard-of-care procedures. The diagnostic performance of the smartphone for cervical intraepithelial neoplasm 1 or worse and cervical intraepithelial neoplasm 2 or worse were evaluated, and the kappa value was calculated to determine the chance corrected agreement of the histologic diagnoses based on the smartphone and colposcopic findings. Results There was a substantial agreement between histologic diagnoses based on the smartphone and colposcopic findings, with a kappa value of 0.67 (95% confidence interval, 0.43–0.90). The sensitivity, specificity, positive predictive value, and negative predictive value of the smartphone in the diagnosis of cervical intraepithelial neoplasm 1 or worse were 0.89 (95% confidence interval, 0.79–0.96), 0.33 (95% confidence interval, 0.08–0.70), 0.91 (95% confidence interval, 0.81-0.97), and 0.30 (95% confidence interval, 0.07–0.65), respectively. The sensitivity, specificity, positive predictive value, and negative predictive value in the diagnosis of cervical intraepithelial neoplasm 2 or worse were 0.92 (95% confidence interval, 0.81–0.98), 0.24 (95% confidence interval, 0.09–0.45), 0.71 (95% confidence interval, 0.58–0.81), and 0.60 (95% confidence interval, 0.26–0.88), respectively. Conclusion We found that there was a substantial agreement between the histologic diagnoses based on the smartphone and colposcopic findings. The smartphone seems to be useful and may be an alternative to colposcopy. |
Databáze: | OpenAIRE |
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