Concomitant Mediterranean spotted fever and systemic lupus erythematosus: a rare case report
| Autor: | Sonia Hammemi, Hajer Ben Brahim, Nada Belhajsalah, S. Daada, Marwa Ben Brahim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Anti-nuclear antibody Serology systemic lupus erythematosus Mediterranean spotted fever erythema nodosum case report immune system diseases Medicine skin and connective tissue diseases Erythema nodosum integumentary system biology business.industry General Medicine medicine.disease biology.organism_classification Rash Dermatology Spotted fever Polyarthritis medicine.symptom business Rickettsia conorii Malar rash |
| Zdroj: | Pan African Medical Journal; Vol. 38 No. 1 (2021) The Pan African Medical Journal |
| ISSN: | 1937-8688 |
| Popis: | Infections are an important cause of morbidity and mortality in Systemic Lupus Erythematosus (SLE). Mediterranean spotted fever (MSF) is a tick-borne disease caused byRickettsia conorii. This infection is endemic in Tunisia with summer seasonality. Herein, the case of a 45 years old woman, admitted to hospital with fever and erythema nodosum. On examination, she had a diffuse skin rash, malar rash, and polyarthritis. Serology demonstratedRickettsia Conoriiinfection. The diagnosis of MSF was made and the patient had a course of doxycycline for 5 days with a prompt improvement of the fever, the skin lesions but she had a persistent malar rash, polyarthritis, and lymphopenia. The immunological profile was positive for antinuclear antibodies (ANA), anti-DNA antibodies, anti-nucleosomes antibodies, and anti-citrullinated protein antibodies (ACPA). The diagnosis of SLE was established. We report the first case of SLE associated with MSF and with erythema nodosum as the initial presentation. |
| Databáze: | OpenAIRE |
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