Periodontitis and breast cancer: A case-control study
| Autor: | Cristiano Susin, Camila Silveira Sfreddo, Carlos Heitor Cunha Moreira, Juliana Maier, Silvia Cardoso de David |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Dentistry Breast Neoplasms 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine medicine Humans Periodontitis General Dentistry business.industry Confounding Smoking Public Health Environmental and Occupational Health Case-control study Reproducibility of Results 030206 dentistry Middle Aged University hospital medicine.disease Clinical attachment loss 030220 oncology & carcinogenesis Case-Control Studies Observational study Smoking status Female business Brazil |
| Zdroj: | Community dentistry and oral epidemiology. 45(6) |
| ISSN: | 1600-0528 |
| Popis: | Objectives The aim of this case-control study was to evaluate the association between periodontitis and breast cancer in a sample of adult Brazilian women. Methods This was a hospital-based study, which included 67 cases and 134 controls (1:2). Women were selected consecutively between April, 2013 and June, 2015 among those attending the Department of Gynecology at the University Hospital of Santa Maria. Cases were selected among women diagnosed with breast cancer (ICD-10 C50), and controls were matched for age (±2 years), and smoking status (never, former and current smoker). Conditional logistic regression was used to model the association between periodontitis and breast cancer with and without adjustment for potential confounders. Four case definitions for periodontitis were used. Results Cases had significantly greater clinical attachment loss than controls (P=.04). After adjusting for important covariates, women diagnosed with periodontitis had two to three times higher odds of breast cancer than women without periodontitis depending on the case definition of periodontitis (P |
| Databáze: | OpenAIRE |
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