A linkage between effectual genes in progression of CRC through canonical and non-canonical TGF-β signaling pathways

Autor:	Marzieh Shirin, Sajedeh Madadi, Noshad Peyravian, Zahra Pezeshkian, Leili Rejali, Masoumeh Hosseini, Afshin Moradi, Binazir Khanabadi, Ghazal Sherkat, Hamid Asadzadeh Aghdaei, Ehsan Nazemalhosseini-Mojarad
Rok vydání:	2022
Předmět:	Adult Male Cancer Research Hematology General Medicine Middle Aged Prognosis Immunohistochemistry ErbB Receptors Young Adult Gene Expression Regulation Oncology Transforming Growth Factor beta Disease Progression Humans Female Colorectal Neoplasms Wnt Signaling Pathway Aged
Zdroj:	Medical Oncology. 39
ISSN:	1559-131X 1357-0560
Popis:	Different molecular signaling pathways have been involved in the incidence and progression of CRC. We aimed to examine the correlation between eight candidate genes, including TFGβ, SMAD2, SMAD4, RhoA, EGFR, MAP2K1, MTA1, and LEF1 in the progression of colorectal cancer (CRC) and their association with clinicopathological variables and CRC patients prognosis. Immunohistochemistry and quantitative real-time polymerase chain reaction (qRT-PCR) analysis 2
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e030bc3d140f6fd5ffac499866b28f93 https://doi.org/10.1007/s12032-021-01634-3 Zobrazit plný text záznamu Full text from SpringerLink