Comparative efficacy of Diazepam, Ketamine, and Diazepam-Ketamine combination for sedation or anesthesia in cockerel chickens
Autor: | Ruth Ndagimba, Peter Shaba, Helen Yarubi Yisa, Muhammad Abdullahi Mahmud, Usman Yahaya Zubairu, Silas Ndagi, James Gana |
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Rok vydání: | 2014 |
Předmět: |
Diazepam
lcsh:Veterinary medicine General Veterinary medicine.drug_class business.industry Sedative Sedation Pharmacology Body weight Ketamine-Diazepam combination Full recovery Cockerel chicken Anesthesia medicine lcsh:SF600-1100 Ketamine Animal Science and Zoology medicine.symptom business Ketamine HCl medicine.drug |
Zdroj: | Journal of Advanced Veterinary and Animal Research, Vol 1, Iss 3, Pp 107-113 (2014) |
ISSN: | 2311-7710 |
Popis: | The comparative efficacy of Diazepam, Ketamine, and Ketamine-Diazepam combination was assessed in adult chickens. The chickens (n=30) were divided into three equal groups (G-1, G-2 and G-3), and were administered with Diazepam dosed at 0.5 mg/kg body weight (b.wt.), Ketamine HCL dosed at 20 mg/kg b.wt., and Ketamine HCL (dosed at 10 mg/kg b.wt.) combined with Diazepam (dosed at 2 mg/kg b.wt.) through intramuscular (IM) route. The means of induction period, duration of sedation or anesthesia, full recovery period and duration of analgesia were significantly (p≤0.05) differed among the groups. Also, the clinical and hematological parameters measured before and after the sedation or anesthesia within the groups were found to be differed significantly (p≤0.05) from each other. It was concluded that Diazepam dosed at 0.5 mg/kg b.wt. (IM) can be used in cockerels. However, combination of Ketamine (at 10 mg/kg IM)-Diazepam (at 2 mg/kg b.wt. IM) is preferably recommended as this combination is comparatively safer, and minimizes the pains elicited from the surgical procedure of using Diazepam alone. |
Databáze: | OpenAIRE |
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