Acupuncture for Patients With Migraine
| Autor: | Susanne Jürgens, Michael Hammes, Andrea Streng, Stefan N. Willich, Andrea Hoppe, Stephan Wagenpfeil, V. Pfaffenrath, Dieter Melchart, Klaus Linde, Benno Brinkhaus, Wolfgang Weidenhammer, Claudia M. Witt |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Randomization Vascular disease business.industry Migraine Disorders Acupuncture Therapy General Medicine medicine.disease Confidence interval Surgery law.invention Clinical trial Migraine Randomized controlled trial law Anesthesia medicine Acupuncture Humans Female Headaches medicine.symptom business |
| Zdroj: | JAMA. 293:2118 |
| ISSN: | 0098-7484 |
| DOI: | 10.1001/jama.293.17.2118 |
| Popis: | ContextAcupuncture is widely used to prevent migraine attacks, but the available evidence of its benefit is scarce.ObjectiveTo investigate the effectiveness of acupuncture compared with sham acupuncture and with no acupuncture in patients with migraine.Design, Setting, and PatientsThree-group, randomized, controlled trial (April 2002-January 2003) involving 302 patients (88% women), mean (SD) age of 43 (11) years, with migraine headaches, based on International Headache Society criteria. Patients were treated at 18 outpatient centers in Germany.InterventionsAcupuncture, sham acupuncture, or waiting list control. Acupuncture and sham acupuncture were administered by specialized physicians and consisted of 12 sessions per patient over 8 weeks. Patients completed headache diaries from 4 weeks before to 12 weeks after randomization and from week 21 to 24 after randomization.Main Outcome MeasuresDifference in headache days of moderate or severe intensity between the 4 weeks before and weeks 9 to 12 after randomization.ResultsBetween baseline and weeks 9 to 12, the mean (SD) number of days with headache of moderate or severe intensity decreased by 2.2 (2.7) days from a baseline of 5.2 (2.5) days in the acupuncture group compared with a decrease to 2.2 (2.7) days from a baseline of 5.0 (2.4) days in the sham acupuncture group, and by 0.8 (2.0) days from a baseline if 5.4 (3.0) days in the waiting list group. No difference was detected between the acupuncture and the sham acupuncture groups (0.0 days, 95% confidence interval, −0.7 to 0.7 days; P = .96) while there was a difference between the acupuncture group compared with the waiting list group (1.4 days; 95% confidence interval; 0.8-2.1 days; P |
| Databáze: | OpenAIRE |
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