Comparison of Abbreviated MRI and Full Diagnostic MRI in Distinguishing between Benign and Malignant Lesions Detected by Breast MRI: A Multireader Study
| Autor: | Nariya Cho, Jung Min Chang, Bo Ra Kwon, Eun Sil Kim, Woo Kyung Moon, Su Hyun Lee, Ann Yi, Soo Yeon Kim, Su Min Ha |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Breast imaging Contrast Media Breast Neoplasms Malignancy Sensitivity and Specificity 030218 nuclear medicine & medical imaging Lesion 03 medical and health sciences 0302 clinical medicine McNemar's test Breast cancer Sensitivity Radiologists medicine Breast MRI Humans Radiology Nuclear Medicine and imaging Breast Aged Retrospective Studies Area under the curve medicine.diagnostic_test Receiver operating characteristic business.industry Breast Imaging Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging ROC Curve 030220 oncology & carcinogenesis Area Under Curve Specificity Original Article Female Radiology medicine.symptom business |
| Zdroj: | Korean Journal of Radiology |
| ISSN: | 2005-8330 1229-6929 |
| Popis: | Objective To compare the performance of simulated abbreviated breast MRI (AB-MRI) and full diagnostic (FD)-MRI in distinguishing between benign and malignant lesions detected by MRI and investigate the features of discrepant lesions of the two protocols. Materials and Methods An AB-MRI set with single first postcontrast images was retrospectively obtained from an FD-MRI cohort of 111 lesions (34 malignant, 77 benign) detected by contralateral breast MRI in 111 women (mean age, 49.8. ± 9.8; range, 28–75 years) with recently diagnosed breast cancer. Five blinded readers independently classified the likelihood of malignancy using Breast Imaging Reporting and Data System assessments. McNemar tests and area under the receiver operating characteristic curve (AUC) analyses were performed. The imaging and pathologic features of the discrepant lesions of the two protocols were analyzed. Results The sensitivity of AB-MRI for lesion characterization tended to be lower than that of FD-MRI for all readers (58.8–82.4% vs. 79.4–100%), although the findings of only two readers were significantly different (p < 0.05). The specificity of AB-MRI for lesion characterization was higher than that of FD-MRI for 80% of readers (39.0–74.0% vs. 19.5–45.5%, p ≤ 0.001). The AUC of AB-MRI was comparable to that of FD-MRI for all readers (p > 0.05). Fifteen percent (5/34) of the cancers were false-negatives on AB-MRI. More suspicious margins or internal enhancement on the delayed phase images were related to the discrepancies. Conclusion The overall performance of AB-MRI was similar to that of FD-MRI in distinguishing between benign and malignant lesions. AB-MRI showed lower sensitivity and higher specificity than FD-MRI, as 15% of the cancers were misclassified compared to FD-MRI. |
| Databáze: | OpenAIRE |
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