Increased fat and polyunsaturated fatty acid content in sow gestation diet has no effect on gene expression in progeny during the first 7 days of life

Autor: P. Bikker, A. Smit-Heinsbroek, Johanna M.J. Rebel, H.P.D. Fijten, M.A. Smits, H. Zwolschen, de Astrid Greeff, S.A. Vastenhouw, E. Bruininx, P. Zetteler
Rok vydání: 2015
Předmět:
0301 basic medicine
Animal Nutrition
Swine
animal diseases
Soybean oil
Dierenwelzijn en gezondheid
Food Animals
Pregnancy
Gene expression
chemistry.chemical_classification
Meal
Bacteriologie
Gene Expression Regulation
Developmental

food and beverages
Bacteriology
Host Pathogen Interaction & Diagnostics

04 agricultural and veterinary sciences
Fish oil
Diervoeding
Polyunsaturated fatty acid
Prenatal Exposure Delayed Effects
Programming
Fatty Acids
Unsaturated

Gestation
Pigs
Animal Nutritional Physiological Phenomena
Female
Sugar beet
Wageningen Livestock Research
Animal Breeding & Genomics
food.ingredient
Offspring
Biology
03 medical and health sciences
food
Animal science
Animals
Animal Health & Welfare
Host-Microbe Interactomics
Fokkerij & Genomica
Nutrition
Host Pathogen Interaction & Diagnostics
business.industry
0402 animal and dairy science
Bacteriology
Maternal Nutritional Physiological Phenomena
biology.organism_classification
Animal Feed
Dietary Fats
040201 dairy & animal science
Host Pathogen Interactie & Diagnostiek
Diet
Biotechnology
030104 developmental biology
Animals
Newborn

chemistry
Bacteriologie
Host Pathogen Interactie & Diagnostiek

WIAS
Pregnancy
Animal

Animal Science and Zoology
business
Zdroj: Journal of Animal Physiology and Animal Nutrition, 100(1), 127-135
Journal of Animal Physiology and Animal Nutrition 100 (2016) 1
ISSN: 0931-2439
DOI: 10.1111/jpn.12345
Popis: The ‘developmental origins of health and disease’ hypothesis proposes not only that we are what we eat, but also that we could be what our parents ate. Here, we aimed to improve health and performance of young piglets via maternal diets based on the hypothesis that maternal nutritional interventions change metabolic programming in piglets, reflected by differential gene expression early in life. Therefore, sows were fed either a regular diet, based on barley, wheat and wheat by-products, sugar beet pulp, palm oil and oilseed meal, or a high-fat (HF) diet consisting of the regular diet supplemented with an additional amount of 3.5% soybean oil and 1% fish oil at the expense of palm oil and wheat. Performance results, physiological parameters and gene expression in liver of piglets and blood of piglets and sows at day 7 after farrowing from both diet groups were compared. The HF diet tended to enhance growth rate of the offspring in the first week of life. No significant differences in gene expression in liver tissue and blood could be detected between the two groups, neither with whole-genome microarray analysis, nor with gene specific qPCR analysis. In this study, the feeding of a high-fat diet with increased amounts of polyunsaturated fatty acid (PUFA) to gestating sows under practical farm settings did not induce significant changes in gene expression in sows and offspring.
Databáze: OpenAIRE