Increased fat and polyunsaturated fatty acid content in sow gestation diet has no effect on gene expression in progeny during the first 7 days of life
Autor: | P. Bikker, A. Smit-Heinsbroek, Johanna M.J. Rebel, H.P.D. Fijten, M.A. Smits, H. Zwolschen, de Astrid Greeff, S.A. Vastenhouw, E. Bruininx, P. Zetteler |
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Rok vydání: | 2015 |
Předmět: |
0301 basic medicine
Animal Nutrition Swine animal diseases Soybean oil Dierenwelzijn en gezondheid Food Animals Pregnancy Gene expression chemistry.chemical_classification Meal Bacteriologie Gene Expression Regulation Developmental food and beverages Bacteriology Host Pathogen Interaction & Diagnostics 04 agricultural and veterinary sciences Fish oil Diervoeding Polyunsaturated fatty acid Prenatal Exposure Delayed Effects Programming Fatty Acids Unsaturated Gestation Pigs Animal Nutritional Physiological Phenomena Female Sugar beet Wageningen Livestock Research Animal Breeding & Genomics food.ingredient Offspring Biology 03 medical and health sciences food Animal science Animals Animal Health & Welfare Host-Microbe Interactomics Fokkerij & Genomica Nutrition Host Pathogen Interaction & Diagnostics business.industry 0402 animal and dairy science Bacteriology Maternal Nutritional Physiological Phenomena biology.organism_classification Animal Feed Dietary Fats 040201 dairy & animal science Host Pathogen Interactie & Diagnostiek Diet Biotechnology 030104 developmental biology Animals Newborn chemistry Bacteriologie Host Pathogen Interactie & Diagnostiek WIAS Pregnancy Animal Animal Science and Zoology business |
Zdroj: | Journal of Animal Physiology and Animal Nutrition, 100(1), 127-135 Journal of Animal Physiology and Animal Nutrition 100 (2016) 1 |
ISSN: | 0931-2439 |
DOI: | 10.1111/jpn.12345 |
Popis: | The ‘developmental origins of health and disease’ hypothesis proposes not only that we are what we eat, but also that we could be what our parents ate. Here, we aimed to improve health and performance of young piglets via maternal diets based on the hypothesis that maternal nutritional interventions change metabolic programming in piglets, reflected by differential gene expression early in life. Therefore, sows were fed either a regular diet, based on barley, wheat and wheat by-products, sugar beet pulp, palm oil and oilseed meal, or a high-fat (HF) diet consisting of the regular diet supplemented with an additional amount of 3.5% soybean oil and 1% fish oil at the expense of palm oil and wheat. Performance results, physiological parameters and gene expression in liver of piglets and blood of piglets and sows at day 7 after farrowing from both diet groups were compared. The HF diet tended to enhance growth rate of the offspring in the first week of life. No significant differences in gene expression in liver tissue and blood could be detected between the two groups, neither with whole-genome microarray analysis, nor with gene specific qPCR analysis. In this study, the feeding of a high-fat diet with increased amounts of polyunsaturated fatty acid (PUFA) to gestating sows under practical farm settings did not induce significant changes in gene expression in sows and offspring. |
Databáze: | OpenAIRE |
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