Method comparison for 241Am emergency urine bioassay
| Autor: | Anthony DiNardo, Karima Benkhedda, Nadereh St-Amant, Raymond Ko, Chunsheng Li, Baki Sadi, Gary H. Kramer, Gerry Moodie |
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| Rok vydání: | 2010 |
| Předmět: |
Urinalysis
Sample (material) Urine Mass Spectrometry medicine Bioassay Radiology Nuclear Medicine and imaging Sample preparation Radiometry Inductively coupled plasma mass spectrometry Radioisotopes Americium Radiation Chromatography Radiological and Ultrasound Technology medicine.diagnostic_test Liquid scintillation counting Public Health Environmental and Occupational Health Reproducibility of Results General Medicine Repeatability Gamma Rays Scintillation Counting Environmental science Biological Assay Chromatography Liquid |
| Zdroj: | Radiation Protection Dosimetry. 141:228-232 |
| ISSN: | 1742-3406 0144-8420 |
| Popis: | 241Am is one of the high-risk radionuclides that might be used in a terrorist attack. 241Am in urine bioassay can identify the contaminated individuals who need immediate medical intervention and decontamination. This paper compares three methods for the measurement of 241Am in urine, namely liquid scintillation counting (LSC), inductively coupled plasma mass spectrometry (ICP-MS) and gamma spectrometry (GS), at two levels, 20 and 2 Bq l(-1). All three methods satisfied the ANSI N13.30 radio-bioassay criteria for accuracy and repeatability. ICP-MS offered the best sensitivity and fastest sample turnaround; however, the ICP-MS system used in this work may not be available in many bioassay laboratories. LSC and GS are more commonly available instruments. GS requires minimal or no sample preparation, which makes it a good candidate method. Moreover, the sample throughput can be significantly improved if the GS and LSC methods are automated. |
| Databáze: | OpenAIRE |
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