Phialemoniopsis limonesiae sp. nov. causing cutaneous phaeohyphomycosis in an immunosuppressed woman
| Autor: | Bart Kraak, P. Valladares, Pedro W. Crous, Chloé Alberto, L. W. Hou, L. Toutous Trellu, D. Alvarez Martinez, B. Ninet, A. Riat, Caroline Schuhler |
|---|---|
| Přispěvatelé: | Westerdijk Fungal Biodiversity Institute, Westerdijk Fungal Biodiversity Institute - Food and Indoor Mycology, Westerdijk Fungal Biodiversity Institute - Evolutionary Phytopathology |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Posaconazole Epidemiology Itraconazole 030106 microbiology Immunology Fungus Microbiology 03 medical and health sciences deep cutaneous phaeohyphomycosis Virology Drug Discovery Phialemoniopsis Biopsy medicine a new taxon ddc:616 Voriconazole Bioavailability itraconazole immunosuppression biology medicine.diagnostic_test A new taxon General Medicine Sordariomycetes biology.organism_classification 030104 developmental biology Infectious Diseases Cutaneous Phaeohyphomycosis Parasitology Deep cutaneous phaeohyphomycosis Opportunistic fungal infections opportunistic fungal infections Immunosuppression Research Article medicine.drug |
| Zdroj: | Emerging Microbes and Infections, 10(1), 400-406. Nature Publishing Group Emerging Microbes & Infections article-version (VoR) Version of Record Emerging Microbes & Infections, Vol. 10, No 1 (2021) pp. 400-406 |
| ISSN: | 2222-1751 |
| DOI: | 10.1080/22221751.2021.1892458 |
| Popis: | Rare or opportunistic fungal infections are mostly described in immunosuppressed patients. We present a case of a cutaneous phaeohyphomycosis that developed on the dorsal foot in an immunosuppressed woman suffering from AIDS, caused by a novel Phialemoniopsis species. It clinically presented as an indurated violaceous plaque, surmounted by nodules exuding a sero-purulent discharge. A filamentous fungus was isolated from pus and cutaneous biopsy. ITS and LSU sequences phylogenetically resolved the fungus as an unknown species of Phialemoniopsis, which is an unresolved family within Sordariomycetes. In this study we describe the new species as Phialemoniopsis limonesiae, which clusters on a single branch clearly separated from its closest phylogenetic neighbours. This new strain showed low MIC to itraconazole, voriconazole and posaconazole. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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