Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome
| Autor: | Beatriz Dietl, Desirée Henares, Lucía Boix-Palop, Carmen Muñoz-Almagro, Javier Garau, Esther Calbo |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Medicine (General) Rinofaringe Aparell respiratori -- Malalties Microbiologia Aparato respiratorio -- Enfermedades Pneumònia Disease Microorganismes medicine.disease_cause Microbiología nasopharynx 0302 clinical medicine Antibiotics 030212 general & internal medicine Infecciones Pneumococs General Medicine Pneumococcus Pneumococcal infections medicine.anatomical_structure Streptococcus pneumoniae Perspective Medicine Infection Microorganismos Microorganisms 616.2 Antibiòtics invasive pneumococcal disease Microbiology 03 medical and health sciences R5-920 Neumonía medicine microbiota Microbiome Antibióticos Related factors business.industry Rhinopharynx Pneumonia medicine.disease pneumococcal infections Nasofaringe Respiratory system -- Diseases 030104 developmental biology Immunology Etiology Infecció business Respiratory tract |
| Zdroj: | Frontiers in Medicine, Vol 8 (2021) Frontiers in Medicine |
| Popis: | Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main aetiological agent of community-acquired pneumonia (CAP). In the last decades, several factors related to the host, the microorganism and the antibiotic therapy have been investigated to identify risk factors associated with the development of invasive pneumococcal disease (IPD). Nevertheless, these factors themselves do not explain the risk of developing disease or its severity. Recently, some studies have focused on the importance of nasopharyngeal (NP) microbiome and its relation to respiratory health. This review presents existing evidence of the potential role of NP microbiome in the development of IPD. |
| Databáze: | OpenAIRE |
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