Contamination levels of human pharmaceutical compounds in French surface and drinking water

Autor: Olivier Thomas, B. Le Bot, S. Mompelat
Přispěvatelé: Laboratoire d'étude et de recherche en environnement et santé (LERES), École des Hautes Études en Santé Publique [EHESP] (EHESP)
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Ozone
010504 meteorology & atmospheric sciences
MESH: Pharmaceutical Preparations
chemistry.chemical_element
Fresh Water
010501 environmental sciences
Management
Monitoring
Policy and Law
01 natural sciences
Iodinated contrast media
chemistry.chemical_compound
Adsorption
Water Supply
medicine
Chlorine
Water Pollution
Chemical
Humans
MESH: Water Supply
0105 earth and related environmental sciences
[SDV.EE.SANT]Life Sciences [q-bio]/Ecology
environment/Health
MESH: Humans
Chemistry
Drinking Water
Public Health
Environmental and Occupational Health
General Medicine
Contamination
MESH: Water Pollution
Chemical
6. Clean water
3. Good health
MESH: France
MESH: Water Pollutants
Chemical
Pharmaceutical Preparations
Environmental chemistry
MESH: Fresh Water
Water treatment
France
Surface water
MESH: Drinking Water
MESH: Environmental Monitoring
Water Pollutants
Chemical
Activated carbon
medicine.drug
Environmental Monitoring
Zdroj: Journal of Environmental Monitoring
Journal of Environmental Monitoring, Royal Society of Chemistry, 2011, 13 (10), pp.2929-39. ⟨10.1039/c1em10335k⟩
Journal of Environmental Monitoring, 2011, 13 (10), pp.2929-39. ⟨10.1039/c1em10335k⟩
ISSN: 1464-0325
1464-0333
DOI: 10.1039/c1em10335k⟩
Popis: International audience; The occurrence of 20 human pharmaceutical compounds and metabolites from 10 representative therapeutic classes was analysed from resource and drinking water in two catchment basins located in north-west France. 98 samples were analysed from 63 stations (surface water and drinking water produced from surface water). Of the 20 human pharmaceutical compounds selected, 16 were quantified in both the surface water and drinking water, with 22% of the values above the limit of quantification for surface water and 14% for drinking water). Psychostimulants, non-steroidal anti-inflammatory drugs, iodinated contrast media and anxiolytic drugs were the main therapeutic classes of human pharmaceutical compounds detected in the surface water and drinking water. The results for surface water were close to results from previous studies in spite of differences in prescription rates of human pharmaceutical compounds in different countries. The removal rate of human pharmaceutical compounds at 11 water treatment units was also determined. Only caffeine proved to be resistant to drinking water treatment processes (with a minimum rate of 5%). Other human pharmaceutical compounds seemed to be removed more efficiently (average elimination rate of over 50%) by adsorption onto activated carbon and oxidation/disinfection with ozone or chlorine (not taking account of the disinfection by-products). These results add to the increasing evidence of the occurrence of human pharmaceutical compounds in drinking water that may represent a threat to human beings exposed to a cocktail of human pharmaceutical compounds and related metabolites and by-products in drinking water.
Databáze: OpenAIRE
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