Ultrasound-Based Quantification of Fibrosis and Steatosis with a New Software Considering Transient Elastography as Reference in Patients with Chronic Liver Diseases
| Autor: | Felix Bende, Roxana Șirli, Raluca Lupușoru, Radu Cotrau, Alina Popescu, Victor Bâldea, Ioan Sporea, Alexandru Popa |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Liver Cirrhosis Male Acoustics and Ultrasonics Biophysics 03 medical and health sciences 0302 clinical medicine Liver steatosis Liver stiffness Fibrosis medicine Humans Radiology Nuclear Medicine and imaging In patient Ultrasonography Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Ultrasound Middle Aged medicine.disease Fatty Liver Cross-Sectional Studies 030220 oncology & carcinogenesis Elasticity Imaging Techniques Female 030211 gastroenterology & hepatology Elastography Steatosis business Transient elastography Nuclear medicine Software |
| Zdroj: | Ultrasound in Medicine & Biology. 47:1692-1703 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/j.ultrasmedbio.2021.02.029 |
| Popis: | The goal of this study was to evaluate the performance of two new ultrasound-based techniques (ShearWave PLUS elastography [2-D-SWE PLUS], SSp PLUS Imaging [SSp PLUS]) implemented on the Aixplorer Mach 30 ultrasound system (Supersonic Imagine, Aix-en-Provence, France) for the non-invasive assessment of liver steatosis and fibrosis, using transient elastography (TE) with the controlled attenuation parameter (CAP) as reference. This monocentric cross-sectional study included 133 consecutive adult patients with chronic hepatopathies. Liver stiffness and steatosis were evaluated in the same session using the techniques mentioned above. An excellent correlation was observed between liver stiffness measurements obtained with 2-D-SWE PLUS and TE (r = 0.92, p0.0001). The best cutoff value of 2-D-SWE PLUS for predicting F≥2 was 6.8 kPa; for F≥3, 8.4 kPa; and for F4, 11 kPa. With respect to steatosis evaluation, a strong negative correlation between CAP and SSp PLUS values (r = -0.70, p0.0001) was obtained. The best SSp PLUS cutoff value for predicting steatosis was 1537 m/s. |
| Databáze: | OpenAIRE |
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