Figure S5 from MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis

Autor:	Anthony C. Faber, Sosipatros A. Boikos, Jennifer E. Koblinski, John Glod, Mikhail G. Dozmorov, Janina P. Lewis, Kimberly Swift, Sivapriya Ramamoorthy, Madhavi Puchalapalli, Bin Hu, Benjamin R. Belvin, Krista M. Powell, Colin M. Coon, Mayuri Shende, Carter K. Fairchild, Richard Kurupi, Sheeba Jacob, JinYang Cai, Konstantinos V. Floros
Rok vydání:	2023
DOI:	10.1158/0008-5472.22428798
Popis:	Figure S5. Amplified MYCN sensitizes neuroblastomas to auranofin. Auranofin increases iron and glutathione levels and induces ROS-dependent ferroptotic cell death in MYCN-amplified NBs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0151f83e63d8fe36a1a9eca122e4746 https://doi.org/10.1158/0008-5472.22428798 Zobrazit plný text záznamu