Reference values of dorsal sural sensory nerve action potential: A useful tool to diagnose peripheral neuropathy
| Autor: | Sunil Kumar Jena, Manoranjan Acharya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Snap RT1-120 RX1-681 Nursing Homeopathy medicine.disease Gastroenterology Group A Nerve conduction velocity Group B Peripheral neuropathy medicine.anatomical_structure age Internal medicine medicine Sensory nerve action potential sex sensory nerve action potential reference data business dorsa sural nerve Subclinical infection Sensory nerve |
| Zdroj: | Muller Journal of Medical Sciences and Research, Vol 12, Iss 1, Pp 13-16 (2021) |
| ISSN: | 0975-9727 |
| Popis: | Background: Dorsal sural sensory nerve is the most distal nerve of the lower limb for which its sensory nerve action potential (SNAP) could be helpful for the diagnosis of early and subclinical peripheral neuropathy. The objective of this study was to estimate the age and sex reference data of amplitude (Amp), onset latency (OL), and conduction velocity (CV) of SNAP. Materials and Methods: A prospective cross-sectional study was conducted among 50 healthy subjects (28 male and 22 female). Participants were stratified into Group A (≤50 years) and Group B (>50 years) according to their age. Student's t-test was used to compare the data between Group A and B, between male and female and Pearson correlation was used to analyze the correlation between age and SNAP parameters. Results: OL of Group A and Group B was 2.80 ± 0.36 ms and 3.11 ± 0.55 ms, respectively (P = 0.037). CV of Group A and Group B was 45.6 ± 3.33 m/sec and 39.5 ± 1.17 m/sec, respectively (P = 0.000). Amp of Group A and Group B was 6.63 ± 0.73 μV 4.99 ± 0.47 μV, respectively (P = 0.000). OL of male and female was 2.59 ± 0.28 ms 3.34 ± 0.25 ms, respectively (P = 0.000). Pearson correlation coefficient “r” between “age– OL,” “age– CV,” and “age– Amp” was 0.135 (P = 0.351), −0.759 (P = 0.000), 0.953 (P = 0.000), respectively. Conclusion: This study provides age and sex reference values of dorsal sural SNAP in the eastern part of the Indian population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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