Association between elevated blood glucose level and non-valvular atrial fibrillation: a report from the Guangzhou heart study
Autor: | Li-Hong Tang, Murui Zheng, Hai Deng, Yang Liu, Zu-Yi Fu, Xianzhang Zhan, Shang-Fei He, Zi-Li Liao, Hongtao Liao, Shulin Wu, Xianhong Fang, Wei Wei, Fangzhou Liu, Yumei Xue, Weidong Lin, Lu Fu |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Blood Glucose
Male lcsh:Diseases of the circulatory (Cardiovascular) system Time Factors Prevalence 030204 cardiovascular system & hematology 0302 clinical medicine Blood serum Risk Factors Atrial Fibrillation 030212 general & internal medicine education.field_of_study Age Factors Middle Aged Prognosis Impaired fasting glucose Up-Regulation Population study Female Sex Sample collection Cardiology and Cardiovascular Medicine Research Article Adult China medicine.medical_specialty Population Non-valvular atrial fibrillation Risk Assessment 03 medical and health sciences Sex Factors Internal medicine Glucose Intolerance Type 2 diabetes mellitus medicine Humans education Aged business.industry Odds ratio medicine.disease Confidence interval Cross-Sectional Studies Diabetes Mellitus Type 2 lcsh:RC666-701 Hyperglycemia business Biomarkers |
Zdroj: | BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-8 (2019) BMC Cardiovascular Disorders |
ISSN: | 1471-2261 |
Popis: | Background To estimate the prevalence of elevated blood glucose level (EBG, including type 2 diabetes mellitus and impaired fasting glucose), and its association with non-valvular atrial fibrillation (NVAF) in Guangzhou, China. Methods The population-based follow-up Guangzhou Heart Study collected baseline data from July 2015 to August 2017 among 12,013 permanent residents aged > 35 from 4 Guangzhou districts. Two streets (Dadong and Baiyun) in the Yuexiu District, and one street (Xiaoguwei) and two towns (Xinzao and Nancun) in the Panyu District were chosen as representative of urban and rural areas, respectively. Each participant completed a comprehensive questionnaire, and underwent physical examination, blood sample collection for laboratory testing, electrocardiography, and other evaluations. Multivariable logistic regression analyses were used to estimate the independent association between hyperglycemia and NVAF prevalence. Results The prevalence of EBG in overall study population was 29.9%. Compared with residents without EBG, the odds ratio (OR) for AF among residents with EBG was significantly higher (1.94, 95% confidence interval [CI]: 1.40–2.70, P P = 0.007), and driven by women (OR = 1.80, 95% CI: 1.12–2.91, P = 0.016). Conclusions In Guangzhou, China, prevalence of EBG is high among residents aged > 35 years and associated with a multivariate adjusted increase in prevalence of NVAF overall and in women. |
Databáze: | OpenAIRE |
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