Association between elevated blood glucose level and non-valvular atrial fibrillation: a report from the Guangzhou heart study

Autor: Li-Hong Tang, Murui Zheng, Hai Deng, Yang Liu, Zu-Yi Fu, Xianzhang Zhan, Shang-Fei He, Zi-Li Liao, Hongtao Liao, Shulin Wu, Xianhong Fang, Wei Wei, Fangzhou Liu, Yumei Xue, Weidong Lin, Lu Fu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Blood Glucose
Male
lcsh:Diseases of the circulatory (Cardiovascular) system
Time Factors
Prevalence
030204 cardiovascular system & hematology
0302 clinical medicine
Blood serum
Risk Factors
Atrial Fibrillation
030212 general & internal medicine
education.field_of_study
Age Factors
Middle Aged
Prognosis
Impaired fasting glucose
Up-Regulation
Population study
Female
Sex
Sample collection
Cardiology and Cardiovascular Medicine
Research Article
Adult
China
medicine.medical_specialty
Population
Non-valvular atrial fibrillation
Risk Assessment
03 medical and health sciences
Sex Factors
Internal medicine
Glucose Intolerance
Type 2 diabetes mellitus
medicine
Humans
education
Aged
business.industry
Odds ratio
medicine.disease
Confidence interval
Cross-Sectional Studies
Diabetes Mellitus
Type 2
lcsh:RC666-701
Hyperglycemia
business
Biomarkers
Zdroj: BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Cardiovascular Disorders
ISSN: 1471-2261
Popis: Background To estimate the prevalence of elevated blood glucose level (EBG, including type 2 diabetes mellitus and impaired fasting glucose), and its association with non-valvular atrial fibrillation (NVAF) in Guangzhou, China. Methods The population-based follow-up Guangzhou Heart Study collected baseline data from July 2015 to August 2017 among 12,013 permanent residents aged > 35 from 4 Guangzhou districts. Two streets (Dadong and Baiyun) in the Yuexiu District, and one street (Xiaoguwei) and two towns (Xinzao and Nancun) in the Panyu District were chosen as representative of urban and rural areas, respectively. Each participant completed a comprehensive questionnaire, and underwent physical examination, blood sample collection for laboratory testing, electrocardiography, and other evaluations. Multivariable logistic regression analyses were used to estimate the independent association between hyperglycemia and NVAF prevalence. Results The prevalence of EBG in overall study population was 29.9%. Compared with residents without EBG, the odds ratio (OR) for AF among residents with EBG was significantly higher (1.94, 95% confidence interval [CI]: 1.40–2.70, P P = 0.007), and driven by women (OR = 1.80, 95% CI: 1.12–2.91, P = 0.016). Conclusions In Guangzhou, China, prevalence of EBG is high among residents aged > 35 years and associated with a multivariate adjusted increase in prevalence of NVAF overall and in women.
Databáze: OpenAIRE
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