Trasplante con precursores hematopoyéticos de cordón umbilical en adultos con neoplasias hematológicas en Chile: Serie clínica
| Autor: | Geraldine Melgoza P, Maritsa Betancur B, Elvira Álvarez J, Verónica García V, Héctor Galindo A, Mauricio Ocqueteau T, Marcelo Garrido S, Pablo Bertín C-M, Mirtza Rivera L, Pablo Ramirez, Mauricio Burotto P, Bruno Nervi N, Manuel Alvarez Z, Verónica Jara A, Pelayo Besa de C |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Leukemia Adult patients business.industry medicine.medical_treatment Immunosuppression General Medicine Human leukocyte antigen medicine.disease Gastroenterology Umbilical cord Cord blood stem cell transplantation Transplantation Haematopoiesis Fetal blood medicine.anatomical_structure Immune system Internal medicine Immunology Medicine business |
| Zdroj: | Revista médica de Chile v.137 n.8 2009 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Hematopoietic precursors transplantation is a therapeutic alternative for leukemia, some metabolic diseases and some immune deficiency syndromes. In its allogeneic variety leukemia eradication is based in the conditioning prior to transplantation and the allogran effect against leukemia. Umbilical cord blood is an alternative source of hematopoietic precursors when there are no HLA compatible relatives available. Between 2003 and 2007 we have performed five umbilical cord blood transplant in adult patients in a University hospital. All patients had malignant diseases. Conditioning protocols were ablative in all except in one patient and in all, more than one unit of umbilical cord blood was used. Hematopoietic engraftment was confirmed in all patients and the main complications registered were infectious and associated to immunosuppression. |
| Databáze: | OpenAIRE |
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