A controlled human intervention trial to study protein quality by amino acid uptake kinetics with the novel Lemna protein concentrate as case study
| Autor: | Ingrid M. van der Meer, Govardus A.H. de Jong, Ron Wehrens, Els Oosterink, Ronald T. M. van den Dool, Diederik Esser, Jasper Engel, Jurriaan J. Mes |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
in vivo protein digestibility
duckweed Kinetics Amino acid uptake amino acid uptake Wiskundige en Statistische Methoden - Biometris law.invention 3Rs Randomized controlled trial law Whey protein concentrate Animals Araceae Humans Food science Amino Acids Mathematical and Statistical Methods - Biometris Food Health & Consumer Research VLAG chemistry.chemical_classification Lemna biology Chemistry Area under the curve biology.organism_classification Amino acid Whey Proteins Postprandial Biometris Health & Consumer Research Food Bioscience lipids (amino acids peptides and proteins) Protein quality Food Science |
| Zdroj: | International Journal of Food Sciences and Nutrition 73 (2022) 2 International Journal of Food Sciences and Nutrition, 73(2), 251-262 |
| ISSN: | 0963-7486 |
| Popis: | A human intervention trial was conducted to study amino acid uptake of the novel Lemna protein concentrate (LPC) in comparison to whey (WPC). The study was a cross-over, double-blind, controlled trial in which 12 healthy participants received 20 grams of LPC and WPC in randomised order. The LPC consumption resulted in a significant lower postprandial increase in almost all individual amino acids, total amino acid (TAA) and total essential amino acids (TEAA) compared to WPC based on area under the curve (AUC) calculations. When the AUC after WPC consumption was set at 100%, LPC showed a relative AUC of 60.4% for TAA and 66.3% for the TEAA. Interindividual variation for LPC was high with an uptake of TEAA of LPC compared to WPC ranging from 18.2 to 94.2%. Human intervention trials can partly replace animal trials as they fully reflect the human situation and provide estimates on individual variations. |
| Databáze: | OpenAIRE |
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