Push-pull receptive field organization and synaptic depression: Mechanisms for reliably encoding naturalistic stimuli in V1
| Autor: | Jens eKremkow, Laurent U Perrinet, Cyril eMonier, Jose-Manuel eAlonso, Ad eAertsen, Yves eFregnac, Guillaume S Masson |
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| Přispěvatelé: | PERIGNON, Alain, Institut de Neurosciences de la Timone (INT), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Unité de Neurosciences Information et Complexité [Gif sur Yvette] (UNIC), Centre National de la Recherche Scientifique (CNRS), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), SUNY College of Optometry (SUNY-Optometry), State University of New York (SUNY), Neurobiology and Biophysics, Faculty of Biology, University of Freiburg, Institut de neurosciences cognitives de la méditerranée - UMR 6193 (INCM), Université de la Méditerranée - Aix-Marseille 2-Centre National de la Recherche Scientifique (CNRS), Institut des Neurosciences de Paris-Saclay (Neuro-PSI), Bernstein Center for Computational Neuroscience, Albert-Ludwigs-Universität Freiburg |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Visual perception genetic structures Surround suppression [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology [SDV.NEU.PC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior Neural Inhibition Visual system 0302 clinical medicine Thalamus MESH: Animals Original Research Visual Cortex MESH: Thalamus [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences MESH: Neural Inhibition Sensory coding Excitation/inhibition Sensory Systems medicine.anatomical_structure Cortical Excitability Visual Perception [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] MESH: Cats Psychology MESH: Cortical Excitability Cognitive Neuroscience Neuroscience (miscellaneous) Sensory system lcsh:RC321-571 03 medical and health sciences Cellular and Molecular Neuroscience push-pull receptive field medicine Animals Visual Pathways lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry MESH: Visual Pathways MESH: Visual Perception [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology MESH: Visual Cortex natural visual stimuli 030104 developmental biology Visual cortex Receptive field Cats Neuroscience 030217 neurology & neurosurgery [SDV.NEU.SC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences |
| Zdroj: | Frontiers in Neural Circuits, Vol 10 (2016) Frontiers in Neural Circuits Frontiers in Neural Circuits, 2016, 10, pp.37. ⟨10.3389/fncir.2016.00037⟩ Frontiers in Neural Circuits, Frontiers, 2016, 10, pp.37. ⟨10.3389/fncir.2016.00037⟩ Frontiers in Neural Circuits, Frontiers, 2016, 10, ⟨10.3389/fncir.2016.00037⟩ |
| ISSN: | 1662-5110 |
| DOI: | 10.3389/fncir.2016.00037/full |
| Popis: | International audience; Neurons in the primary visual cortex are known for responding vigorously but with high variability to classical stimuli such as drifting bars or gratings. By contrast, natural scenes are encoded more efficiently by sparse and temporal precise spiking responses. We used a conductance-based model of the visual system in higher mammals to investigate how two specific features of the thalamo-cortical pathway, namely push-pull receptive field organization and fast synaptic depression, can contribute to this contextual reshaping of V1 responses. By comparing cortical dynamics evoked respectively by natural vs. artificial stimuli in a comprehensive parametric space analysis, we demonstrate that the reliability and sparseness of the spiking responses during natural vision is not a mere consequence of the increased bandwidth in the sensory input spectrum. Rather, it results from the combined impacts of fast synaptic depression and push-pull inhibition, the later acting for natural scenes as a form of "effective" feed-forward inhibition as demonstrated in other sensory systems. Thus, the combination of feedforward-like inhibition with fast thalamo-cortical synaptic depression by simple cells receiving a direct structured input from thalamus composes a generic computational mechanism for generating a sparse and reliable encoding of natural sensory events. |
| Databáze: | OpenAIRE |
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