Clinical and radiographic observations from four patients with primary hepatic lymphoma
| Autor: | Zai‑Peng Zhang, Hui‑Juan Hu, Yan‑Juan Qu, Zhi‑Xiong Tian |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Cancer Research
medicine.medical_specialty Pathology Radiography Primary Hepatic Lymphoma hepatic lymphoma Lesion 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) medicine magnetic resonance imaging Pathological medicine.diagnostic_test business.industry non-Hodgkin lymphoma Cancer computed tomography Magnetic resonance imaging Articles General Medicine medicine.disease B symptoms 030220 oncology & carcinogenesis Radiological weapon 030211 gastroenterology & hepatology Radiology medicine.symptom business |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2015.2940 |
| Popis: | The aim of the present study was to delineate the radiographic and clinical features of primary hepatic lymphoma (PHL). Four histopathologically confirmed cases of PHL were analyzed with respect to the radiological, clinical and pathological characteristics. The main clinical manifestations included upper right quadrant pain and lymphoma-associated B symptoms, such as fever, night sweating and weight loss. All the patients had elevated serum levels of lactate dehydrogenase. Furthermore, all the patients underwent plain and enhanced computed tomography examinations, which identified low-density lesions without marked enhancement. Solitary masses were observed in two cases, while multiple focal lesions were noted in one case and diffuse multi-speckled nodules were observed in one case. Two patients underwent abdominal magnetic resonance imaging, which revealed lesions that were hyperintense on T1-weighted imaging (WI) scans and hypointense on T2WI scans, and exhibited slight to moderate enhancement with a dynamic contrast-enhanced protocol. In one case, vessels were visible within the lesion. Therefore, the present study concluded that PHL is a rare condition that exhibits non-specific clinical and radiological features. A combination of imaging results and clinical manifestations can be used to facilitate a diagnosis of PHL. |
| Databáze: | OpenAIRE |
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