Does an abnormally elevated maternal alkaline phosphatase pose problems for the fetus?

Autor: Christopher S. King, Sarah McErlean
Rok vydání: 2019
Předmět:
musculoskeletal diseases
Adult
medicine.medical_specialty
Placenta
Intrauterine growth restriction
Placental insufficiency
03 medical and health sciences
0302 clinical medicine
stomatognathic system
Pregnancy
medicine.artery
Internal medicine
medicine
Humans
Preterm delivery
Fetus
030219 obstetrics & reproductive medicine
Fetal Growth Retardation
business.industry
Cesarean Section
musculoskeletal
neural
and ocular physiology

Umbilical artery
General Medicine
Infant
Low Birth Weight

medicine.disease
musculoskeletal system
Alkaline Phosphatase
Placental Insufficiency
Pregnancy Complications
Low birth weight
Endocrinology
Treatment Outcome
030220 oncology & carcinogenesis
embryonic structures
Alkaline phosphatase
Female
medicine.symptom
business
Biomarkers
Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
Zdroj: BMJ Case Rep
ISSN: 1757-790X
Popis: We report a potential association between an abnormally raised pregnancy level of alkaline phosphatase (ALP) and intrauterine growth restriction (IUGR). There are few reports of women with abnormally high ALP during pregnancy. However, there is work to suggest an association with placental insufficiency, low birth weight and preterm delivery. In conjunction with a rising ALP, fetal IUGR and intermittent absence of umbilical artery end diastolic flow had evolved. A greatly elevated ALP may be a marker for placental insufficiency and IUGR.
Databáze: OpenAIRE