Imaging pediatric gastrointestinal stromal tumor (GIST)
| Autor: | Moriz Herzberg, Sudha A. Anupindi, Kurt Vollert, Meinrad Beer, Thomas Kröncke |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Leiomyosarcoma
Male medicine.medical_specialty Lung Neoplasms Gastrointestinal Stromal Tumors Contrast Media Multimodal Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Positron Emission Tomography Computed Tomography medicine Humans Stage (cooking) Stromal tumor Child neoplasms Paraganglioma Extra-Adrenal PET-CT medicine.diagnostic_test GiST business.industry General Medicine Magnetic Resonance Imaging digestive system diseases Endoscopy Imatinib mesylate Positron emission tomography 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Surgery Female Radiology business Tomography X-Ray Computed Chondroma Contrast-enhanced ultrasound |
| Popis: | Background Gastrointestinal stromal tumors (GIST) are extremely rare in children. Imaging plays a key role in staging and monitoring therapy (surgical and with tyrosine kinase inhibitors). The vast majority of articles addressing imaging of GIST base on adults and are based on CT. The subtype "pediatric GIST" – if at all – is only mentioned in a dependent clause. Although the imaging features in children and adults are similar, histology, clinical course and thus imaging approach are different. Methods A PubMed search using the search terms "Gastrointestinal stromal tumor, GIST, WT GIST, children, pediatric, carney's triad, imaging, staging, follow-up, MRI, CEUS, ultrasonography, Positron emission tomography" was conducted. Studies that reported on laparoscopy, endoscopy and surgical techniques only were excluded. Results Based on our selective literature review, we present alternative radiological imaging strategies using MRI, contrast enhanced ultrasound (CEUS) and PET–CT to stage and follow-up pediatric GIST patients. As pediatric GIST often is a chronic disease, minimizing exposure to ionizing radiation is mandatory. Conclusion MRI, contrast enhanced ultrasound and PET–CT instead of CT are the imaging modalities to evaluate pediatric GIST. Type of study Systematic review Level of evidence III |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|