Resectability, Resections, Survival Outcomes, and Quality of Life in Older Adult Patients with Metastatic Colorectal Cancer (the RAXO-Study)

Autor:	Kaisa Lehtomäki, Leena-Maija Soveri, Emerik Osterlund, Annamarja Lamminmäki, Aki Uutela, Eetu Heervä, Päivi Halonen, Hanna Stedt, Sonja Aho, Timo Muhonen, Annika Ålgars, Tapio Salminen, Raija Kallio, Arno Nordin, Laura Aroviita, Paul Nyandoto, Juha Kononen, Bengt Glimelius, Raija Ristamäki, Helena Isoniemi, Pia Osterlund
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	General Medicine older adults metastatic colorectal cancer metastasectomy liver resection lung resection cytoreductive surgery local ablative therapy oncological treatment health-related quality of life
Zdroj:	Journal of Clinical Medicine; Volume 12; Issue 10; Pages: 3541
ISSN:	2077-0383
DOI:	10.3390/jcm12103541
Popis:	Older adults are underrepresented in metastatic colorectal cancer (mCRC) studies and thus may not receive optimal treatment, especially not metastasectomies. The prospective Finnish real-life RAXO-study included 1086 any organ mCRC patients. We assessed repeated centralized resectability, overall survival (OS), and quality of life (QoL) using 15D and EORTC QLQ-C30/CR29. Older adults (>75 years; n = 181, 17%) had worse ECOG performance status than adults (
Databáze:	OpenAIRE
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