Effects of sleep deprivation on the activity of selected metabolic enzymes in skeletal muscle
| Autor: | Veselková A, Bass A, Andĕl M, E Kuhn, Teisinger J, V Brodan, Vondra K |
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| Rok vydání: | 1981 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology Glycerolphosphate Dehydrogenase Dehydrogenase Citrate (si)-Synthase Malate dehydrogenase chemistry.chemical_compound Malate Dehydrogenase Hexokinase Physiology (medical) Internal medicine Lactate dehydrogenase medicine Humans Citrate synthase Orthopedics and Sports Medicine Glycolysis L-Lactate Dehydrogenase biology Muscles Public Health Environmental and Occupational Health 3-Hydroxyacyl CoA Dehydrogenases Glyceraldehyde-3-Phosphate Dehydrogenases Skeletal muscle General Medicine 3-Hydroxyacyl-CoA Dehydrogenase medicine.anatomical_structure Endocrinology chemistry biology.protein Sleep Deprivation Energy Metabolism Branched-chain alpha-keto acid dehydrogenase complex |
| Zdroj: | European Journal of Applied Physiology and Occupational Physiology. 47:41-46 |
| ISSN: | 1439-6327 0301-5548 |
| DOI: | 10.1007/bf00422481 |
| Popis: | The effect of 120-h sleep deprivation on the activity of selected enzymes of energy metabolism in skeletal muscle was studied in seven healthy volunteers. The results showed a significant decrease in the activity of malate dehydrogenase, citrate synthase, glycerol-3-phosphate dehydrogenase and lactate dehydrogenase. Triosephosphate dehydrogenase, hexokinase, and hydroxyacyl-CoA-dehydrogenase activities showed an insignificant decrease. The findings are indicative of (1) decreased aerobic oxidation capacity; (2) reduced function of reducing-equivalent carriers from cytosol across the mitochondrial membrane; (3) relative accentuation of the non-aerobic glycolytic pathway; (4) a prediabetic type of muscle metabolism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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