Thyroxine concentration in human milk
| Autor: | Bruno Lunenfeld, Joseph Sack, O. Amado |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
medicine.medical_specialty
Time Factors Milk Human business.industry Endocrinology Diabetes and Metabolism Biochemistry (medical) Clinical Biochemistry Postpartum Period Radioimmunoassay Obstetrics and Gynecology General Medicine Biochemistry Thyroxine Endocrinology Animal science Pregnancy Internal medicine Medicine Humans Lactation Euthyroid Female business Postpartum period |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 45(1) |
| ISSN: | 0021-972X |
| Popis: | Thyroxine (T4) concentrations were measured by RIA in 37 milk samples from 19 healthy eutryroid mothers, obtained between 3-165 days postpartum. The mean milk T4 concentration in the first week postpartum was 0.38 +/- 0.07 microgram/100 ml (mean +/- SEM). The mean T4 concentrations between 8 and 48 days rose to 4.27 +/- 0.50 microgram/100 ml (mean +/- SEM), and decreased to 1.11 +/- 0.25 microgram/100 ml (mean +/- SEM) after 50 days postpartum. The data suggest that human milk can provide a significant exogenous source of T4 to the infant. In the hypothyroid infant, the amount of T4 in human milk may delay clinical recognition of the disease. Although this exogenous source of T4 may alleviate the disease, it is insufficient to prevent the detrimetal effects of hypothyroidism. |
| Databáze: | OpenAIRE |
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