Sleep-Disordered Breathing and Pregnancy-Related Cardiovascular Disease
| Autor: | Aaron D. Laposky, Victoria L. Pemberton |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Gestational hypertension
Special Issue Articles medicine.medical_specialty pre-eclampsia Disease 03 medical and health sciences 0302 clinical medicine Sleep Apnea Syndromes Pregnancy Risk Factors Internal medicine mental disorders medicine gestational hypertension Humans Sleep disorder 030219 obstetrics & reproductive medicine business.industry sleep-disordered breathing Infant Newborn Intermittent hypoxia General Medicine medicine.disease nervous system diseases respiratory tract diseases Diabetes Gestational Cardiovascular Diseases Hypertension Cardiology Sleep disordered breathing Breathing Female business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Women's Health |
| ISSN: | 1931-843X |
| Popis: | Sleep-disordered breathing (SDB) is a serious medical condition characterized by intermittent episodes of airflow limitation, intermittent hypoxia, and sleep disturbance triggering a pattern of autonomic dysfunction associated with hypertension, diabetes, and other adverse health conditions. SDB incidence is two to three times higher during pregnancy and is associated with an increased risk of cardiometabolic complications, including pre-eclampsia and gestational diabetes. Treatments to protect breathing during sleep are available, pointing to SDB as a potential therapeutic target to reduce maternal cardiometabolic morbidity. However, in clinical practice, the majority of SDB cases in pregnancy are undiagnosed, indicating a need to improve screening for SDB risk factors and referral for diagnostic testing. Furthermore, definitive clinical trials are needed to determine the extent to which SDB intervention reduces the risk of adverse cardiovascular and neonatal outcomes in pregnancy. This review article discusses an accumulation of research pointing to SDB as a prevalent risk factor for gestational cardiometabolic disease, as well as a potential therapeutic target to reduce cardiometabolic morbidity. |
| Databáze: | OpenAIRE |
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