‘Microalbuminuric anaemia’—The relationship between haemoglobin levels and albuminuria in diabetes
| Autor: | K.A. Abraham, Geoff Gill, H. Mani, A. Olujohungbe, O.R. Adetunji |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Urban Population Cross-sectional study Endocrinology Diabetes and Metabolism Population Renal function urologic and male genital diseases Hemoglobins Young Adult Endocrinology hemic and lymphatic diseases Diabetes mellitus Internal medicine Internal Medicine medicine Albuminuria Humans Diabetic Nephropathies education Aged Aged 80 and over education.field_of_study business.industry Incidence (epidemiology) Anemia General Medicine Middle Aged medicine.disease Cross-Sectional Studies Diabetes Mellitus Type 2 England Cardiovascular Diseases Creatinine Population study Female Microalbuminuria medicine.symptom business Diabetic Angiopathies Glomerular Filtration Rate |
| Zdroj: | Diabetes Research and Clinical Practice. 85:179-182 |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2009.04.028 |
| Popis: | There is an increasing incidence of anaemia in diabetes despite the absence of significant renal impairment.This study set out to determine the prevalence of anaemia in a diabetic population and to explore the relationship between anaemia and urinary albumin excretion in diabetes mellitus. Also, to determine the difference between those with overt nephropathy, microalbuminuria and those without evidence of renal disease.Five hundred and two consecutive diabetes patients were screened for anaemia. Anaemia was defined by World Health Organization criteria (13 g/dl for men and12 g/dl for women). Urinary albumin excretion was determined by urinary albumin creatinine ratio (ACR) from a single urine sample.Anaemia was present in 118 (23.5%) patients. There was a rise in the prevalence of anaemia from 19% in patients with a normal ACR to 29% in those with microalbuminuria and to 41% in macroalbuminuria. This increase in the prevalence of anaemia in microalbuminuria compared to normoalbuminuria was not explained by declining renal function as there was no significant difference in eGFR between the two groups.Anaemia was common in the study population. Early detection and correction of anaemia in diabetes is important for patients at risk of impaired quality of life and increased cardiovascular risk. |
| Databáze: | OpenAIRE |
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