A multicenter observational study on the clinicopathological features of gastric cancer in young patients
| Autor: | Masaya Iwamuro, Daisuke Kawai, Yoshiyasu Kono, Masahiro Takatani, Toshiyoshi Fujiwara, Junichirou Nasu, Takehiro Tanaka, Yoshiro Kawahara, Ryuta Takenaka, Hiromitsu Kanzaki, Takao Tsuzuki, Seiji Kawano, Hiroyuki Okada |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Gastritis Atrophic Male medicine.medical_specialty CA-19-9 Antigen Disease Kaplan-Meier Estimate Gastroenterology Asymptomatic Helicobacter Infections 03 medical and health sciences Young Adult 0302 clinical medicine Surgical oncology Stomach Neoplasms Internal medicine Medicine Humans Neoplasm Staging Retrospective Studies Family Health biology Helicobacter pylori business.industry Age Factors Cancer Hepatology biology.organism_classification medicine.disease Prognosis Colorectal surgery Carcinoembryonic Antigen Pedigree Survival Rate 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female medicine.symptom business Abdominal surgery |
| Zdroj: | Journal of gastroenterology. 54(5) |
| ISSN: | 1435-5922 |
| Popis: | The details of gastric cancer in young patients remain unclear because of the low prevalence of the disease. This study aimed to clarify the clinicopathological features and prognosis of gastric cancer in young patients. From January 2007 to January 2016, patients in their 20s and 30s who were diagnosed with primary gastric cancer at 4 hospitals were enrolled. Their clinical characteristics and prognosis were evaluated. The total number of patients was 72. The median age was 36 years, and the ratio of males to females was 1:1. The dominant histological type was undifferentiated type (66/72, 92%). Helicobacter pylori (H. pylori) was positive in 81% (54/67). Although there were some asymptomatic patients in stages I–III, all stage IV patients had some clinical symptoms at the diagnosis. The percentage of stage IV was significantly higher in patients in their 20s than in those in their 30s (75% vs. 25%, P |
| Databáze: | OpenAIRE |
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