Increased rates of intensive care unit admission in patients with Mycoplasma pneumoniae : a retrospective study
| Autor: | Carlos Hidalgo-Grass, Ran Nir-Paz, Ayman Abu Rmeileh, Abed Bayya, A. Nubani, Allon E. Moses, S. Hoss, Sigal Sviri, P. V. Van Heerden, Avraham Abutbul, Tawfik Khoury |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) Mycoplasma pneumoniae medicine.medical_specialty Adolescent 030106 microbiology medicine.disease_cause Severity of Illness Index law.invention Young Adult 03 medical and health sciences Patient Admission 0302 clinical medicine Risk Factors law Internal medicine Pneumonia Mycoplasma Severity of illness Humans Medicine Hospital Mortality 030212 general & internal medicine Child Aged Retrospective Studies Aged 80 and over business.industry Respiratory disease Retrospective cohort study General Medicine Middle Aged medicine.disease Intensive care unit Surgery Intensive Care Units Pneumonia Infectious Diseases Child Preschool Population Surveillance Concomitant Cohort Female business |
| Zdroj: | Clinical Microbiology and Infection. 22:711-714 |
| ISSN: | 1198-743X |
| DOI: | 10.1016/j.cmi.2016.05.028 |
| Popis: | Mycoplasma pneumoniae is a leading cause of respiratory disease. In the Intensive Care Unit (ICU) setting M. pneumoniae is not considered a common pathogen. In 2010-13 an epidemic of M. pneumoniae-associated infections was reported and we observed an increase of M. pneumoniae patients admitted to ICU. We analysed the cohort of all M. pneumoniae-positive patients' admissions during 2007 to 2012 at the Hadassah-Hebrew University Medical Centre (a 1100-bed tertiary medical centre). Mycoplasma pneumoniae diagnosis was made routinely using PCR on throat swabs and other respiratory samples. Clinical parameters were retrospectively extracted. We identified 416 M. pneumoniae-infected patients; of which 68 (16.3%) were admitted to ICU. Of these, 48% (173/416) were paediatric patients with ICU admission rate of 4.6% (8/173). In the 19- to 65-year age group ICU admission rate rose to 18% (32/171), and to 38.8% (28/72) for patients older than 65 years. The mean APACHE II score on ICU admission was 20, with a median ICU stay of 7 days, and median hospital stay of 11.5 days. Of the ICU-admitted patients, 54.4% (37/68) were mechanically ventilated upon ICU admission. In 38.2% (26/68), additional pathogens were identified mostly later as secondary pathogens. A concomitant cardiac manifestation occurred in up to 36.8% (25/68) of patients. The in-hospital mortality was 29.4% (20/68) and correlated with APACHE II score. Contrary to previous reports, a substantial proportion (16.3%) of our M. pneumoniae-infected patients required ICU admission, especially in the adult population, with significant morbidity and mortality. |
| Databáze: | OpenAIRE |
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