| Autor: |
Lim, Jia Yi Joel, Wee, Rui Wen Bryan, Gandhi, Mihir, Lim, Yee Phong, Tan, Li Nien Michelle, Quek, Swee Chye, Aw, Marion M., Chen, Ching Kit |
| Přispěvatelé: |
Tampere University, Clinical Medicine |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Frontiers in Cardiovascular Medicine. 9 |
| ISSN: |
2297-055X |
| DOI: |
10.3389/fcvm.2022.812680 |
| Popis: |
Aim:We explored the association between preoperative anthropometry and biochemistry, and postoperative outcomes in infants with CHD after cardiac surgery, as infants with congenital heart disease (CHD) often have feeding difficulties and malnutrition.MethodologyThis was a retrospective review of infants (≤ 1-year-old) who underwent congenital heart surgery. Preoperative anthropometryin terms of preoperative weight-for-age z-score (WAZ), length-for-age z-score (LAZ), as well as preoperative serum albumin and hemoglobin concentrations, were evaluated against 6-month mortality, and morbidity outcomes including postoperative complications, vasoactive inotrope score, duration of mechanical ventilation, length of stay in the pediatric intensive care unit and in hospital, using the logistic regression or median regression models accounting for infant-level clustering.ResultsOne hundred and ninety-nine operations were performed in 167 infants. Mean gestational age at birth was 38.0 (SD 2.2) weeks (range 26 to 41 weeks). Thirty (18.0%) infants were born preterm (p = 0.02), and 6-month mortality (odds ratio 2.38; p = 0.008) following CHD surgery. There was no meaningful association between the other preoperative variables and other outcomes.ConclusionMore than 50% of infants with CHD undergoing cardiac surgery within the first year of life have feeding difficulties, of which 22% require to be tube-fed. Low preoperative WAZ is associated with increased postoperative complications and 6-month mortality. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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