Association Between Trace Element Status and Depression in HTLV-1-Infected Patients: a Retrospective Cohort Study

Autor: Amir Hooshang Mohammadpour, Habibollah Esmaily, Zahra Meshkat, Susan Darroudi, Parvin Zamani, Batool Tayefi, Shima Tavalaei, Samaneh Abolbashari, Gordon A. Ferns, Zahra Khashyarmanesh, Hamideh Moalemzadeh Haghighi, Majid Ghayour-Mobarhan, Najmeh Ahangari, Maryam Tayefi
Rok vydání: 2018
Předmět:
Zdroj: Biological trace element research. 191(1)
ISSN: 1559-0720
Popis: Depression and Anxiety are two important public health problems that are known to be associated with viral infections. The association between the intake of nutrients such as zinc and copper with symptoms of depression has been studied previously. The aim of the current study was to investigate the association between depression with human T cell lymphotropic virus type 1 (HTLV-1) infection and serum content of zinc and copper in a large Iranian population cohort. The study population consisted of 279 HTLV-1-positive patients who were identified after recruitment as part of a large cohort study: the Mashhad Stroke and Heart Association Disorder (MASHAD) study. They were divided into two groups of diagnosed with or without depression based on their symptoms. Serum zinc and copper levels of all subjects were measured using the flame atomic absorption spectrometry. The population sample comprised of 279 individuals infected with HTLV-1 of whom 192 (68.8%) were women. The mean serum zinc in the group with and without depression was 78.69 ± 13.79 μg/dl and 86.87 ± 19.44 μg/dl, respectively (p
Databáze: OpenAIRE