AFP-producing Xp11 translocation renal cell carcinoma: Case report and review of the literature

Autor: Hui-Zhi Zhang, Su-Ying Wang
Rok vydání: 2021
Předmět:
Zdroj: Current Problems in Cancer. 45:100689
ISSN: 0147-0272
Popis: Alpha-fetoprotein (AFP) is a useful tumor marker for hepatocellular carcinomas and yolk sac tumors. Rare extrahepatic visceral malignancies may be associated with AFP production and those exhibiting a hepatoid differentiation by morphology and immunohistochemical are classified as hepatoid adenocarcinoma. Renal cell carcinoma (RCC) producing AFP is a rare entity. To date, only one case of AFP-producing Xp11 translocation RCC has been reported. We reported another case of Xp11 translocation RCC, in which the tumor cells displayed strong immunostaining for AFP, HepPar1, and GPC-3. Additionally, the other published cases are reviewed.
Databáze: OpenAIRE