Behaviour of IgG antibody avidity for the antigen and of IgA antibody in active cytomegalovirus, Epstein-Barr virus, herpes simplex virus and human herpes virus 6 infections. Adaptation of a commercial test
| Autor: | María del Carmen Maroto, José Gutiérrez, J. Peirón, Gonzalo Piédrola, M. Rodríguez |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Microbiology (medical) Human cytomegalovirus Herpesvirus 4 Human Herpesvirus 6 Human Antibody Affinity Congenital cytomegalovirus infection Cytomegalovirus medicine.disease_cause Sensitivity and Specificity Herpesviridae Virus medicine Humans Simplexvirus Serologic Tests Avidity Antigens Bacterial biology business.industry Herpesviridae Infections medicine.disease Epstein–Barr virus Virology Immunoglobulin A Infectious Diseases Herpes simplex virus Child Preschool Immunoglobulin G Immunology biology.protein Antibody business |
| Zdroj: | Journal of Infection. 35:25-30 |
| ISSN: | 0163-4453 |
| DOI: | 10.1016/s0163-4453(97)90881-1 |
| Popis: | The clinical value of specific IgA and IgG antibody avidity to herpes simplex virus, cytomegalovirus, Epstein-Barr virus and human herpes virus 6 for the detection of active disease and primary infection, respectively, was evaluated. The IgG avidity test, with a break point of 55%, for the detection of primary infection, and of the IgA test for the detection of disease, were associated with a sensitivity of 97% and 64%, respectively; specificity of 100% and 82%; a positive predictive value of 100% and 76%; and a negative predictive value of 96% and 72%, respectively. |
| Databáze: | OpenAIRE |
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