Complex interactions in the regulation of trypanosome mitochondrial gene expression
Autor: | Donna J. Koslowsky |
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Rok vydání: | 2009 |
Předmět: |
Genetics
Mitochondrial DNA biology Polyadenylation DNA Kinetoplast Trypanosoma brucei brucei fungi Protozoan Proteins Kinetoplastida Mitochondrion biology.organism_classification Genome Mitochondria Genes Mitochondrial Infectious Diseases Gene Expression Regulation Gene expression Animals Parasitology Guide RNA Adaptation |
Zdroj: | Trends in Parasitology. 25:252-255 |
ISSN: | 1471-4922 |
DOI: | 10.1016/j.pt.2009.03.008 |
Popis: | Trypanosomes undergo extreme physiological changes to adapt to different environments as they cycle between hosts. Adaptation to the different environments has evolved an energy metabolism involving a mitochondrion with an unusual genome. Recently, Aphasizhev and colleagues have identified two new protein complexes, a mitochondrial polyadenylation complex and a guide RNA stabilization complex, that provide novel insights into the coordinated expression of the mitochondrial genome. |
Databáze: | OpenAIRE |
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