Fabrication of Resveratrol-Loaded Whey Protein–Dextran Colloidal Complex for the Stabilization and Delivery of β-Carotene Emulsions
| Autor: | Luyu Gao, Yuzhu Zhang, Yuexiang Liu, Jiang Yi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Whey protein Nanoparticle Whey protein isolate Hydrophobic effect 03 medical and health sciences chemistry.chemical_compound Drug Delivery Systems 0404 agricultural biotechnology Drug Stability Stilbenes 030109 nutrition & dietetics biology Chemistry Osmolar Concentration Dextrans 04 agricultural and veterinary sciences General Chemistry beta Carotene 040401 food science Whey Proteins Dextran Chemical engineering Resveratrol Ionic strength Emulsion biology.protein Nanoparticles Emulsions Chemical stability General Agricultural and Biological Sciences Hydrophobic and Hydrophilic Interactions |
| Zdroj: | Journal of Agricultural and Food Chemistry. 66:9481-9489 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/acs.jafc.8b02973 |
| Popis: | The effects of resveratrol (RES)-loaded whey protein isolate (WPI)-dextran nanocomplex on the physicochemical stability of β-carotene (BC) emulsions were evaluated. WPI-dextran was prepared by Maillard-based glycation and confirmed with gel electrophoresis and OPA assay. WPI-RES and WPI-dextran-RES nanoparticles were prepared with a simple nanocomplexation protocol. Fluorescence spectra indicated that hydrophobic interaction was the main driving force for the WPI-dextran-RES nanocomplex. Spherical and uniformly dispersed structures as well as nanoscale Z-average size (100 nm) were confirmed for WPI-RES and WPI-dextran-RES nanocomplex with DLS and TEM. The Z-average diameter of emulsions with WPI-dextran conjugate was remarkably lower than that with WPI. Environmental stress (ionic strength, heat, and pH) and storage stability were pronouncedly improved. The chemical stability of BC with WPI-dextran-RES and WPI-RES was also remarkably enhanced when exposed to UV light and thermal treatment. The advantages of the WPI-dextran-RES colloidal complex may provide a better alternative to effectively protect and deliver hydrophobic nutraceuticals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|