Lipoatrophic panniculitis of children
| Autor: | Iliana L. Aguirre-Martinez, Antonio Torrelo |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Nosology
Abdominal pain medicine.medical_specialty Panniculitis Dermatology Malaise Pathogenesis 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Medicine Humans Child Lipoatrophy 030203 arthritis & rheumatology business.industry medicine.disease Lipoatrophic panniculitis Methotrexate medicine.symptom Atrophy business medicine.drug Rare disease |
| Zdroj: | Clinics in dermatology. 39(2) |
| ISSN: | 1879-1131 |
| Popis: | Idiopathic lipoatrophic panniculitis of children is a rare disease of childhood, characterized by repeated attacks of tender subcutaneous nodules followed by the development of permanent lipoatrophy, often seen on the arms and legs, in association with fever, malaise, and other less common clinical manifestations such as abdominal pain or arthralgia. The pathogenesis is unknown, and autoimmune origins, chromosomal alterations, and other causes have been proposed. The nosology of this condition is confusing in the literature, and the precise diagnosis still relies on a combination of clinicopathologic and laboratory assessments. Methotrexate may be recommended to minimize disease progression and morbidity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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