Presence of Biofilms on Polyurethane-Coated Breast Implants: Preliminary Results
| Autor: | Andrej Trampuz, Gerhard Pierer, Ulrich M. Rieger, Gregor F. Raschke, Reno Frei, Alexander Pattiss, Gabriel Djedovic |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Breast Implants Polyurethanes 030106 microbiology Biomedical Engineering Capsular contraction 03 medical and health sciences Propionibacterium acnes Coated Materials Biocompatible medicine Humans Prospective cohort study Breast Implantation General Dentistry Retrospective Studies biology business.industry Biofilm Capsular contracture Middle Aged biology.organism_classification Surgery Biofilms Female Implant business |
| Zdroj: | Journal of Long-Term Effects of Medical Implants. 26:237-243 |
| ISSN: | 1050-6934 |
| DOI: | 10.1615/jlongtermeffmedimplants.2016016851 |
| Popis: | Polyurethane-coated breast implants seem to be associated with lower medium- and long-term capsular contracture rates in comparison to textured or smooth implant surfaces. Although the etiology of capsular contracture is uncertain, bacterial biofilms have been suggested to trigger chronic peri-implant inflammation, eventually leading to capsular contracture. It is unknown whether polyurethane-coated implants are less prone to biofilm colonization than other implant surfaces. We extracted data from patient records included in a prospective cohort between 2008 and 2011. All patients who underwent removal of polyurethane-coated implants were included in this current study and screened for presence of biofilms by sonication. In addition, implant- and patient-related data were analyzed. Of the ten included polyurethane-coated breast implants, six had been inserted for reconstructive purposes and four for aesthetic reasons. The median implant indwelling time was 28.3 mo. Overall, sonication cultures were positive in 50% of implants. Propionibacterium acnes and coagulase-negative staphylococci were the predominant pathogens isolated from biofilm cultures. Like other implant surfaces, polyurethane-coated implants are prone to biofilm colonization. Further investigations are needed to determine why capsular contracture rates seem to be lower in polyurethane implants than in other implant surfaces. Notably, in this study, 40% of the implants were explanted from breasts with severe capsular contracture. |
| Databáze: | OpenAIRE |
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