A Slow-Digesting, Low-Glycemic Load Nutritional Beverage Improves Glucose Tolerance in Obese Pregnant Women Without Gestational Diabetes
| Autor: | Paul T. Seed, S. Barr, Helen R. Murphy, Lucilla Poston, Nashita Patel, Rahat Maitland, Jose Maria Lopez Pedrosa, Barbara Marriage, Christina Sherry, Llenalia Garcia Fernandez, Ricardo Rueda |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Blood Glucose Endocrinology Diabetes and Metabolism Physiology 030209 endocrinology & metabolism Body Mass Index Beverages 03 medical and health sciences 0302 clinical medicine Endocrinology Pregnancy Diabetes mellitus Glucose Intolerance Glycemic load Dietary Carbohydrates medicine Humans Obesity 030212 general & internal medicine Glucose tolerance test medicine.diagnostic_test business.industry Glycemic Load Glucose Tolerance Test medicine.disease Diet Gestational diabetes Diabetes Gestational Medical Laboratory Technology Glycemic index Female business Body mass index |
| Zdroj: | Maitland, R, Patel, N, Barr, S, Sherry, C, Marriage, B, Seed, P, Fernandez, L G, Pedrosa, J M L, Murphy, H, Rueda, R & Poston, L 2018, ' A Slow-Digesting, Low-Glycemic Load Nutritional Beverage Improves Glucose Tolerance in Obese Pregnant Women Without Gestational Diabetes ', Diabetes Technology and Therapeutics, vol. 20, no. 10, pp. 672-680 . https://doi.org/10.1089/dia.2018.0102 |
| ISSN: | 1557-8593 1520-9156 |
| Popis: | BACKGROUND: Obesity is a risk factor for gestational diabetes (gestational diabetes). Low-glycemic index diets attenuate hyperglycemia. We designed a study to determine whether a slow-digesting, low-glycemic load (SD-LGL) beverage improves glucose tolerance in obese pregnant women without GDM.METHODS: This was a 3-arm comparison study comparing the effects of an SD-LGL nutritional beverage (glycemic load [GL] 730), an isocaloric control beverage (GL 1124), and habitual diet on glycemia in obese pregnant women. Sixteen women (mean body mass index 37 kg/m2) were recruited at 24-28 weeks to receive either the SD-LGL or eucaloric control beverage. This was consumed with breakfast and as a midafternoon snack over 2 days with a controlled diet. Following a 2-day washout period of habitual diet, women completed 2 days on the alternative beverage with controlled diet. A 10-h fast preceded each intervention phase. Twenty-four hour glucose was measured using continuous glucose monitoring.RESULTS: Consumption of the lower GL beverage was associated with improved measures of glycemia, compared with the control beverage and habitual diet at different time periods. Glucose estimates for control versus SD-LDL at 24 h (0.23 mmol/L [0.16 to 0.31], P CONCLUSION: A slow-digesting, low-glycemic nutritional beverage may facilitate improved glucose control in obese pregnant women. To address potential benefit for clinical outcomes, a randomized controlled trial is warranted. |
| Databáze: | OpenAIRE |
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