Association between THRSP Gene Polymorphism and Fatty Acid Composition in Milk of Dairy Cows
| Autor: | Jacek Golińczak, Witold Stanisław Proskura, Arkadiusz Terman, Andrzej Dybus, Daniel Polasik |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Veterinary medicine Biology fatty acids Article polymorphism 03 medical and health sciences symbols.namesake Polymorphism (computer science) Genotype SF600-1100 THRSP Gene Food science Gene Dairy cattle Sanger sequencing milk THRSP General Veterinary 0402 animal and dairy science dairy cattle food and beverages 04 agricultural and veterinary sciences 040201 dairy & animal science Breed De novo synthesis 030104 developmental biology QL1-991 symbols Animal Science and Zoology Zoology |
| Zdroj: | Animals, Vol 11, Iss 1144, p 1144 (2021) Animals : an Open Access Journal from MDPI Animals Volume 11 Issue 4 |
| ISSN: | 2076-2615 |
| Popis: | Thyroid hormone-inducible hepatic protein is involved in the de novo synthesis of fatty acids in the lactating mammary gland. Different variants of the gene that encodes this protein may be associated with its different activity. The primary aim of this study was to find polymorphism in the THRSP gene and estimate the relationship between individual genotypes and fatty acid composition in milk. Investigations were carried out on 224 cows represented by two breeds—Jersey (n = 80) and Polish Holstein-Friesian (n = 144). Polymorphism in THRSP was detected by Sanger sequencing however, genotypes were determined by the PCR-RFLP method. It was shown that the analyzed variant had a significant (p < 0.05) influence on palmitic and stearic fatty acids as well as on fatty acids with a chain length of 14, 16, and 6–16 in Jersey breed and on caproic, palmitic, myristoleic, and palmitoleic fatty acids in H-F. Obtained results indicated that analyzed SNP in bovine THRSP gene (rs42714482) may be considered as a potential marker for fatty acid composition in milk |
| Databáze: | OpenAIRE |
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