| Autor: |
Cornelis E.C.A. Hop, Peter S. Dragovich, Andrew G. Polson, Keyang Xu, Katherine R. Kozak, Dian Su, Jack D. Sadowsky, Thomas H. Pillow, Yong Ma, S. Cyrus Khojasteh, Shang-Fan Yu, Donglu Zhang |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1535-7163.22504461.v1 |
| Popis: |
Table S1. (A) Quantitation of PBD in tumors and (B) total antibody in plasma of xenograft mice following intravenously administration of ADC conjugates. Figure S1. (A-D) Correlation (X-Y plots) of tumor growth inhibition with intratumor PBD exposures after intravenous administration of corresponding ADCs A1-A4. Figure S2. Disulfide stability and immolation for payload release in incubations of ADCs A1-A4 in the presence of cysteine at pH 5.5 or 7.0. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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