Clinical Evaluations of the Ischemic Core in Acute Ischemic Stroke Using Modified Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Scores by Ischemic Reversibility Using the Signal Intensity
| Autor: | Hirokazu Nishiyama, Naotsugu Toki, Naoyuki Nakao, Hiroyuki Matsumoto, Daisuke Izawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Core (anatomy) medicine.diagnostic_test business.industry reversivility ischemic core Computed tomography Neurosciences. Biological psychiatry. Neuropsychiatry medicine.disease signal intensity ratio medicine Neurology (clinical) Radiology cardiovascular diseases Signal intensity Cardiology and Cardiovascular Medicine business Stroke Acute ischemic stroke modified diffusion-weighted imaging-the alberta stroke program early computed tomography score Diffusion MRI RC321-571 |
| Zdroj: | JNET, Vol 15, Iss 9, Pp 574-582 (2021) |
| ISSN: | 2186-2494 1882-4072 |
| Popis: | Objective: Early recanalization of acute stroke caused by large vessel occlusion (LVO) may improve high signal intensity (HSI) on diffusion-weighted imaging (DWI). In this study, we investigated whether subtraction of reversible ischemic lesions (RIL) from the HSI lesions on DWI improves the diagnostic accuracy for the ischemic core. Methods: A total of 35 patients from April 2013 and December 2019 were included in this study. These patients presented acute ischemic stroke due to anterior circulation LVO and underwent thrombectomy. All patients underwent DWI within 48 hours after thrombectomy. HSI ratios were calculated, and compared between ischemic lesions and contralateral normal tissue. Ischemic lesions with improvement in the HSI ratio from initial to postoperative DWI were defined as RIL. Based on a receiver operating characteristic (ROC) curve analysis that compared the HSI ratio of all ischemic lesions, the cutoff value of HSI ratio of RILs was calculated. Results: In all, 127 ischemic lesions were identified in 35 patients. HSI ratios of RILs were significantly lower than those of irreversible ischemic lesions (IILs) (p |
| Databáze: | OpenAIRE |
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