Autologous Bone Marrow Derived Stem Cells for the Treatment of Multiple Sclerosis
| Autor: | Abi Chahine N, Rashed J, Tarek Wehbe, Elias N, Hilal R |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Oncology medicine.medical_specialty Multiple Sclerosis medicine.medical_treatment Stem cells Autologous bone marrow Peripheral blood mononuclear cell 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Stem cell transplantation for articular cartilage repair Progressive multiple sclerosis Expanded Disability Status Scale business.industry Multiple sclerosis Cell Biology Stem-cell therapy Autologous bone medicine.disease The expanded disability status scale 030104 developmental biology Mononuclear cells Original Article Stem cell business 030217 neurology & neurosurgery Developmental Biology |
| Zdroj: | International Journal of Stem Cells |
| ISSN: | 2005-5447 2005-3606 |
| Popis: | Stem cell therapy, an evolving, progressive field of therapeutics has shown several successes in areas where classic treatments failed to prevent or stop disability. Starting in 2009, twenty two sequential patients with progressive Multiple Sclerosis (MS) courses were treated with Autologous Bone Marrow Mononuclear stem cells (BM-MNSCs). The cells were given both intravenously and intrathecally. Using the Expanded Disability Status Scale (EDSS) score for evaluation, our data indicates that the majority of the patients benefited on the average one point on the scale. This paper adds to the body of evidence suggesting the safety and efficacy of autologous BM-MNSCs in the treatment of MS and awaits validation through larger, randomized studies. |
| Databáze: | OpenAIRE |
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