Calciphylaxis in simultaneous liver-kidney transplantation
| Autor: | Ari J. Cohen, D. A. Bruce, B. Vincent, Humberto Bohorquez, N. Chamorro, C. Staffeld, A. Moiz, George E. Loss, J. Garces, N. K. Davis, Trevor Reichman, Ian Carmody |
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| Rok vydání: | 2014 |
| Předmět: |
Nephrology
Male medicine.medical_specialty medicine.medical_treatment Liver transplantation Sepsis Internal medicine medicine Immunology and Allergy Humans Pharmacology (medical) Kidney transplantation Transplantation Calciphylaxis business.industry Hepatology Middle Aged medicine.disease Kidney Transplantation Surgery Liver Transplantation Clinical research Female business |
| Zdroj: | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15(4) |
| ISSN: | 1600-6143 |
| Popis: | We present four patients who underwent simultaneous liver–kidney transplantation (SLK) and were diagnosed with calciphylaxis, also known as calcific uremic arteriolopathy (CUA). Common characteristics included high MELD scores (mean 35.2 ± 4.8) and advanced renal disease (duration range 6–44 weeks). CUA was diagnosed within the first 2 months post-SLK based on clinical features. Severe morbidity and prolonged hospital stay were observed and one of the patients died secondary to sepsis. Treatment included metabolic support, wound care, calcium level correction and use of sodium thiosulphate. CUA should be considered in the presence of painful dermatologic changes in patients status post SLK. |
| Databáze: | OpenAIRE |
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