[Decreased Heart Rate Variability in Sickle Cell Anemia as Effect of Pulmonary Arterial Hypertension]
| Autor: | Talantbek Batyraliev, F. Akgul, Fatih Yalçin, Sidorenko Ba, E. Gali, Ergün Seyfeli, A. G. Arystan, Fettser Dv, Tunzale Seydaliyeva |
|---|---|
| Přispěvatelé: | Zonguldak Bülent Ecevit Üniversitesi |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Decreased heart rate genetic structures Hypertension Pulmonary Early detection Blood Pressure Anemia Sickle Cell Significant negative correlation 03 medical and health sciences 0302 clinical medicine Heart Rate Internal medicine pulmonary hypertension medicine Heart rate variability Humans In patient 030304 developmental biology 0303 health sciences business.industry Healthy subjects heart rate variability Arrhythmias Cardiac 030229 sport sciences medicine.disease Pulmonary hypertension Sickle cell anemia nervous system Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Kardiologiia. 59(4) |
| ISSN: | 0022-9040 |
| Popis: | WOS: 000474853700006 PubMed: 31002038 Decreased heart rate variability (HRV) is associated with increased mortality risk in various diseases. The objective of this investigation: to study HRV in patients with sickle cell anemia (SCA) and to assess the effect of pulmonary arterial hypertension (PAH) on HRV in these patients. Materials and methods. HRV registration and Doppler echocardiographic assessment of systolic pulmonary arterial pressure (PAP) was carried out in 61 stable patients with SCA and 24 healthy subjects. Results. Low frequency power (LFP) and high frequency power (HFP) were decreased in SCA patients compared to healthy subjects. Among SCA patients, PAH patients had lower LFP and HFP than patients without PAH. In SCA patients, systolic PAP showed significant negative correlation with LFP and HFP. Conclusion. HRV is significantly decreased in SCA patients, especially in those with PAH. HRV may be particularly useful in early detection of PAH patients who may have worse prognosis and higher mortality risk. |
| Databáze: | OpenAIRE |
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