Effects of preweaning environmental enrichment on hippocampus-dependent learning and memory in developing rats

Autor:	Chonghuai Yan, Le Zhong, Ying Tian, Xiaoming Shen, Cheng-Qiu Lu
Rok vydání:	2017
Předmět:	0301 basic medicine MAPK/ERK pathway medicine.medical_specialty Long-Term Potentiation Hippocampus Nerve Tissue Proteins Weaning Environment Motor Activity Biology Rats Sprague-Dawley 03 medical and health sciences 0302 clinical medicine Memory Internal medicine Avoidance Learning medicine Animals Learning Phosphorylation Extracellular Signal-Regulated MAP Kinases Environmental enrichment Kinase General Neuroscience Body Weight Long-term potentiation Cytoskeletal Proteins Electrophysiology 030104 developmental biology Endocrinology Exploratory Behavior Excitatory postsynaptic potential Signal transduction Neuroscience 030217 neurology & neurosurgery
Zdroj:	Neuroscience Letters. 640:117-122
ISSN:	0304-3940
Popis:	Previous studies have shown that environmental enrichment (EE) improves learning and memory in adult animals. However, the effects of preweaning EE (preEE) on hippocampus-dependent learning and memory as well as its possible mechanisms are poorly understood. Here we report that preEE enhanced the exploratory activity in rats immediately after weaning, and the EE group showed greater performance in a passive avoidance task than the control group (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df534c31d9b8e2a787fda25e8395469f https://doi.org/10.1016/j.neulet.2016.12.053 Zobrazit plný text záznamu Full Text from ScienceDirect