Metabolic syndrome after kidney transplantation
| Autor: | Michele Piva, Odino Garizzo, Fabrizio Stoppa, Giuseppe Bucciante, Annamaria Bernardi, Paolo Scaramuzzo, Tecla Pati, Domenico Santoro, Vincenzo Savica, Guido Bellinghieri |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Medicine (miscellaneous) Blood lipids Postoperative Complications Sex Factors Risk Factors Internal medicine Hyperlipidemia medicine Prevalence Humans Obesity Risk factor Kidney transplantation Metabolic Syndrome Nutrition and Dietetics business.industry Middle Aged medicine.disease Kidney Transplantation Postmenopausal syndrome Transplantation Endocrinology Nephrology Kidney Failure Chronic Female Metabolic syndrome Menopause business |
| Zdroj: | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 19(1) |
| ISSN: | 1532-8503 |
| Popis: | Metabolic syndrome (MS) can be linked to the progression of chronic renal transplant dysfunction (CRTD). Hyperfiltration in transplanted patients is a further risk factor for MS and for the progression of CRTD. Many studies show in kidney-transplanted subjects a prevalence of MS at 60% after 6 years posttransplantation. We studied 182 patients (126 men and 56 women) with functioning renal transplant in Messina and Rovigo Renal Units. In our patients we saw at 6 years postkidney transplant in men a prevalence of MS at 20% (NCEPATPIII criteria) or 30% (Rovigo-Messina more strict criteria), and women at 6 years posttransplantation a prevalence of MS at 25% (NCEPATPIII criteria) or 50% (Rovigo-Messina criteria). In our patients, the period of graft function was over 15 years. This result is due to continued follow-up of metabolic parameters and to moderate protein (0.8–0.9 g/kg/day), low lipid, and low caloric intake. These strategies permit the avoidance of hyperfiltration, the reduction of hyperlipidemia and obesity. Special attention is due to women 50–65 years old. In these patients the prevalence of metabolic syndrome 6 years posttransplant is very high (60%). Postmenopausal syndrome is an additional risk factor for MS, atherosclerosis, and the progression of CRTD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|