Diabetic Peripheral Neuropathic Pain: Recognition and Management
Autor: | B. Eliot Cole |
---|---|
Rok vydání: | 2007 |
Předmět: |
medicine.medical_specialty
Pain Thiophenes Duloxetine Hydrochloride Norepinephrine (medication) chemistry.chemical_compound Diabetic Neuropathies Diabetes mellitus Epidemiology medicine Humans Duloxetine Intensive care medicine Depression (differential diagnoses) business.industry General Medicine medicine.disease Antidepressive Agents Diabetic Foot Anesthesiology and Pain Medicine Peripheral neuropathy chemistry Anesthesia Neurology (clinical) Reuptake inhibitor business medicine.drug |
Zdroj: | Pain Medicine. 8:S27-S32 |
ISSN: | 1526-4637 1526-2375 |
DOI: | 10.1111/j.1526-4637.2007.00349.x |
Popis: | The occurrence of diabetic peripheral neuropathy (DPN) is linked to poor glycemic control over time. While most people never develop diabetic peripheral neuropathic pain (DPNP) as a consequence of DPN, enough of them do that we must have effective options for the management of this disabling condition. Two years ago there were no formally approved medications for the treatment of DPNP, and now there are two medications with Food and Drug Administration approval for DPNP. One of these medications, duloxetine has been established to significantly improve pain and to address depression by its reuptake inhibition of norepinephrine and serotonin. This article examines the epidemiology of DPNP, its underlying pathogenesis, necessary evaluation methods, and treatment options available with a focus on the role of duloxetine. |
Databáze: | OpenAIRE |
Externí odkaz: |